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Douglas, D.W., Kesson, A.M. and King, N.J.C. (1994) CTL Recognition of West Nile Virus-Infected Fibroblasts Is Cell Cycle Dependent and Is Associated with Virus-Induced Increases in Class I MHC Antigen Expression. Immunology, 82, 561-570.

has been cited by the following article:

• TITLE: Using a Collateral Damage Model to Explain Survival Data in West Nile Virus Infections

  AUTHORS: James K. Peterson, Alison M. Kesson, Nicholas J. C. King

  KEYWORDS: Auto Immune Responses, West Nile Virus, Host Survival Models, MHC-I Upregulation, IFN-γ Upregulation, Free Antigen Levels

  JOURNAL NAME: Advances in Microbiology, Vol.6 No.4, April 7, 2016

  ABSTRACT: Simulation code for a model of the adaptive immune response seen in flavivirus infections is used to explain the immunopathological consequences seen in West Nile Virus virus (WNV) infections. We use a model that specifically handles the differences in how the virus infects resting cells, the G0 state, versus dividing cells, the G1 state, which includes vastly increased MHC-I upregulation for resting cells over dividing cells. The simulation suggests how the infection progresses in a one host model and the results shed insight into the unusual survival curve data obtained for this infection: there is an increase in health even though viral load has increased.