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Yoon, D.Y., Chu, J., Chandler, C., Hiyama, S., Thompson, J.E. and Hines, O.J. (2002) Human Cytokine Levels in Nonperforated versus Perforated Appendicitis: Molecular Serum Markers for Extent of Disease? The American Surgeon, 68, 1033-1037.

has been cited by the following article:

• TITLE: The Role of C-Reactive Protein, Granulocyte Colony Stimulating Factor and Total Antioxidant Capacity in Diagnosis of Acute Appendicitis

  AUTHORS: Barış Sevinç, Ahmet Okuş, Serden Ay, Nergis Aksoy, Recep Demirgül

  KEYWORDS: Acute Appendicitis, C-Reactive Protein, Granulocyte Colony Stimulating Factor, Total Anti-Oxidant Capacity

  JOURNAL NAME: Surgical Science, Vol.7 No.3, March 25, 2016

  ABSTRACT: Background and Aim: Despite the fact that acute appendicitis is the most common surgical emergency all around the world, its diagnosis is still based on clinical evaluation and accuracy of the diagnosis depending on experience. The aim of this study is to evaluate the role of inflammatory markers in diagnosis of acute appendicitis. Material and Method: The study includes 77 cases with histopathologically proven acute appendicitis and 17 control cases. Blood samples were obtained from all cases and C-reactive protein (CRP), Granulocyte Colony Stimulating Factor (G-CSF) and Total Antioxidant Capacity (TAC) were measured. Findings: In cases with acute appendicitis, CRP and G-CSF levels were found to be related to acute appendicitis; however, TAC was not affected by the disease process. Moreover, CRP and G-CSF levels were correlated with the disease severity. Conclusion: Both CRP and G-CSF can be used in diagnosis of acute appendicitis. Furthermore, increased CRP level can be a marker to show advanced cases. However, G-CSF is not an effective marker to show disease severity.