TITLE:
Synthesis and Hydrophilic Performance of Poly(Lactic Acid)-Poly(Ethylene Glycol) Block Copolymers
AUTHORS:
Gang Xu, Sihao Chen, Xiao Yan, Chunyu Yang, Zhichang Chen
KEYWORDS:
Lactide, Poly(Lactic Acid)-Poly(Ethylene Glycol) (PLA-PEG), Prepare, Hydrophily
JOURNAL NAME:
American Journal of Analytical Chemistry,
Vol.7 No.3,
March
24,
2016
ABSTRACT: Lactide was
synthesized using lactic acid and stannous octoate as raw material and
catalyst, respectively. Poly(lactic acid)-poly(ethylene glycol) (PLA-PEG) was
prepared by lactide and poly (ethylene glycol) (PEG) via ring-opening
polymerization. The most appropriate technological conditions of synthesis of
lactide were researched in the paper. The copolymers were measured by Infrared
spectroscopy (IR) and 1H nuclear magnetic resonance (1H
NMR). The results proved that the lactide and PLA-PEG were synthesized successfully.
Hydrophilic performance of the copolymer was measured by a water contact angle
tester after prepared into a flat membrane. The water contact angle changed
from 81.5? to 71.6?, which proved that the hydrophily of PLA-PEG was better
than PLA.