TITLE:
Detection and Quantification of Anti-Inflammatory Cytokine in Sera and Urine of Sudanese Patients Infected with Schistosoma haematobium
AUTHORS:
A. Hammad, Manahil Nouri, Abdelbagi Alfadil, H. A. Musa, M. A. Osman, A. Bashir, Nawal Eltayeb Omer, Yasir Hassan, A. Alfarazdeg, A. Mustafa
KEYWORDS:
Schistosoma haematobum, Interleukin, ELISA
JOURNAL NAME:
Open Journal of Medical Microbiology,
Vol.6 No.1,
March
23,
2016
ABSTRACT: Cytokines have been in focus of scientific in for more than decade now. Analyzing their expression has enabled a better understanding of pathogenesis of various diseases. Moreover, they are now for beyond their stage when they were of interest for pathophysiological research. In the present study, we used an assay to anti-inflammatory cytokines. One hundred and thirty sera and urine from egg positive individuals and 42 samples of healthy individuals in Eldeum locality—an endemic area of S. haematobum and 28 healthy individuals from non-endemic area were tested. Concentration of IL5 and IL10 is reverse. IL5 is low in serum but high in urine before treatment and high in serum and low in urine after treatment. IL10 is high in serum, low in urine before treatment and low in serum, high in urine after treatment.