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de Silva, A. P., Gunaratne, H. Q. N., Gunnlaugsson, T., Huxley, A. J. M., McCoy, C. P., Rademacher, J. T., Rice, T. E. (1997) SigHnaling recognition events with fluorescent sensors and switchesH, Chemical Reviews, 97, 1515-1566.

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• TITLE: A fluorescence turn-on Hg2+ probe based on rhodamine with excellent sensitivity and selectivity in living cells

  AUTHORS: Li Jiang, Ling Wang, Bo Zhang, Gui Yin, Rui-Yong Wang

  KEYWORDS: Fluorescence Probe; Mercury; Rhodamine; Yeast; HeLa cell

  JOURNAL NAME: Open Journal of Inorganic Chemistry, Vol.1 No.2, July 29, 2011

  ABSTRACT: A highly sensitive and selective Hg2+ probe 4 based on rhodamine-b was developed and characterized. In consideration of environmental and biological application, we connected a water soluble receptor group (sulfonated β-naphtol) and rhodamine-b together through hydrazine hydrate in high yield. The result turns out that this compound not only exhibits excellent sensitivity and selectivity toward Hg2+, but also shows well cell permeability and compatibility in vitro.