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Du, J., Fan, J., Peng, X., Sun, P., Wang, J., Li, H., Sun, S. (2010) A Hnew fluorescent chemodosimeter for Hg2+: selectivity, sensitivity, and resistance to Cys and GSHH, Organic Letters, 12, 476-479.

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• TITLE: A fluorescence turn-on Hg2+ probe based on rhodamine with excellent sensitivity and selectivity in living cells

  AUTHORS: Li Jiang, Ling Wang, Bo Zhang, Gui Yin, Rui-Yong Wang

  KEYWORDS: Fluorescence Probe; Mercury; Rhodamine; Yeast; HeLa cell

  JOURNAL NAME: Open Journal of Inorganic Chemistry, Vol.1 No.2, July 29, 2011

  ABSTRACT: A highly sensitive and selective Hg2+ probe 4 based on rhodamine-b was developed and characterized. In consideration of environmental and biological application, we connected a water soluble receptor group (sulfonated β-naphtol) and rhodamine-b together through hydrazine hydrate in high yield. The result turns out that this compound not only exhibits excellent sensitivity and selectivity toward Hg2+, but also shows well cell permeability and compatibility in vitro.