TITLE:
Risk Factors for Chemotherapy-Induced Leukopenia in Patients with Lung Cancer
AUTHORS:
Hongyan Jin, Xiaoya Chen, Wei He, Qian Liu, Zexiong Wei, Jinjun Li
KEYWORDS:
Chemotherapy-Induced Leucopenia, Risk Factors, Lung Cancer
JOURNAL NAME:
International Journal of Clinical Medicine,
Vol.7 No.3,
March
18,
2016
ABSTRACT: Objective: This analysis was conducted to clarify risk factors for chemotherapy-induced leukopenia (CIL) in lung cancer. Methods: A retrospective study was conducted on data from 358 patients with lung cancer who received chemotherapy. Results: Among 358 cases of lung cancer who received chemotherapy, a total of 240 patients experienced CIL, rate was 67%. The demographic data including gender (P = 0.795), age (P = 0.134), presence of selected chronic comorbidities (P = 0.23) were not significantly different in the two groups. The weight loss rate, PS score, sub-normal pre-WBC level, sub-normal pre-PLT level, and the cycle of chemotherapy were significantly different between the groups (P