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Yu, S.Y., Lee, I.S., Jung, S.H., Lee, Y.M., Lee, Y.R., Kim, J.H., Sun, H. and Kim, J.S. (2013) Caffeoylated Phenylpropanoid Glycosides from Brandisia hancei Inhibit Advanced Glycation End Product Formation and Aldose Reductase in Vitro and Vessel Dilation in Larval Zebrafish in Vivo. Planta Medica, 79, 1705-1709.
http://dx.doi.org/10.1055/s-0033-1351101

has been cited by the following article:

• TITLE: Validated UPLC/Q-TOF-MS Method for Determination of Poliumoside in Rat Plasma and Its Application to Pharmacokinetic Study

  AUTHORS: Hao Qian, Danyi Lu, Wan Li, Xiaotong Zhou, Baojian Wu, Zhiguo Ma

  KEYWORDS: Poliumoside, UPLC/Q-TOF-MS, Rat Plasma, Pharmacokinetics

  JOURNAL NAME: American Journal of Analytical Chemistry, Vol.7 No.3, March 15, 2016

  ABSTRACT: Poliumoside is the main active constituent of Callicarpa kwangtungensis Chun (CK), a traditional Chinese medicine for management of hemostasis. In this study, a rapid and selective ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UPLC/ Q-TOF-MS) method was developed and validated to quantify poliumoside in rat plasma. The targeted analytes in rat plasma were prepared through protein-precipitation method using 10% trichloroacetic acid (TCA). The chromatographic separation was performed on a Waters BEH C18 column (2.1 × 100 mm, 1.7 μm) by acetonitrile-water containing 0.1% formic acid. The calibration curve was linear over the range of 50 - 10,000 ng/mL (r2 > 0.99). The intra-day or inter-day precision was less than 7.97% and accuracy was within ?7.00% - 3.36%. The developed method was successfully applied to pharmacokinetic study of poliumoside in rat plasma. Although being rapidly absorbed (Tmax ≤ 30 min), poliumoside was poorly bioavailable after oral administration (the absolute bioavailability was only 0.69%).