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Shinohara, N., Nonomura, N., Kimura, G., et al. (2013) A Randomized Multicenter Phase II Trial on Efficacy of a Hydrocolloid Dressing Containing Ceramide with a Low-Friction External Surface for Hand-Foot Skin Reaction Caused by Sorafenib in Patients with Renal Cell Carcinoma. Proceedings of the Annual Meeting of the American Society of Clinical Oncology, 31, abstr 9623.

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• TITLE: Relationship between Self-Care and Hand Foot Syndrome Specific Quality of Life in Cancer Patients

  AUTHORS: Naoko Mikoshiba, Noriko Yamamoto-Mitani, Kazuki Sato, Yukari Yaju, Mitsunori Miyashita

  KEYWORDS: Chemotherapy, Hand-Foot Syndrome, Neoplasm, Quality of Life, Supportive Care

  JOURNAL NAME: Open Journal of Nursing, Vol.6 No.2, February 18, 2016

  ABSTRACT: Purpose: The purpose of this study was to describe adherence to self-care for hand-foot syndrome (HFS) and the relationship between self-care and health-related quality of life (QOL). Methods: A cross-sectional study was conducted on 105 consecutive outpatients with HFS. To assess self-care for HFS and QOL, the participants were asked to complete self-care and HFS-14 (hand-foot syndrome specific QOL) questionnaires, respectively. Multiple regression models were used to identify the relationship between self-care and QOL. Results: Adherence to self-care for HFS was low, less than 50% for most of the items. Multivariate analysis revealed that poorer self-care (βs = -0.19; P = 0.03), depressive symptoms (βs = 0.43; P βs = 0.20; P = 0.04) were independent predictors of poorer QOL scores. Conclusions: We have identified a need for further research to develop effective programs of self-care in HFS.