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Tanimoto, M., Kanazawa, A., Hirose, T., Yoshihara, T., Kobayashi-Kimura, S., Nakanishi, R., Tosaka, Y., Sasaki-Omote, R., Kudo-Fujimaki, K., Komiya, K., Ikeda, F., Someya, Y., Mita, T., Fujitani, Y. and Watada, H. (2015) Comparison of Sitagliptin with Nateglinide on Postprandial Glucose and Related Hormones in Drug-Naive Japanese Patients with Type 2 Diabetes Mellitus: A Pilot Study. Journal of Diabetes Investigation, 6, 560-566.
http://dx.doi.org/10.1111/jdi.12338

has been cited by the following article:

• TITLE: Association between Hyperglycemia, C-Reactive Protein and Other Risk Factors in Patients at Cardiovascular Risk

  AUTHORS: Sandra Maria Barbalho, Ricardo José Toffano, Marcelo Dib Bechara, Karina Rodrigues Quesada, Marie Oshiiwa, Claudemir Gregório Mendes, Marcia Rocha Gabaldi

  KEYWORDS: Hyperglycemia, C-Reactive Protein, Angiography, Castelli Index, Lipids

  JOURNAL NAME: Journal of Diabetes Mellitus, Vol.6 No.1, February 4, 2016

  ABSTRACT: Type 2 diabetes (DM2) is a syndrome characterized by postprandial hyperglycemia normally due to peripheral resistance to insulin and accounts for approximately 90% of diabetes cases worldwide and it is usually related to dyslipidemia, overweight/obesity and physical inactivity and increase in the risk of cardiovascular disease. This study aimed to compare the metabolic and inflammatory profile of hyperglycemic with non-hyperglycemic subjects in a group of patients undergoing coronary arteriography. Our group of patients showed that 63.16% presented glycaemia above 99 mg/dL (from the hyperglycemic patients, 31 individuals were classified as glucose intolerant and 29 as diabetic). Significant differences were found for glycaemia, LDL-c (Low Density Lipoprotein), and hs-CRP (high sensitivity C reactive protein) levels. Nevertheless it is possible to observe that patients with higher glycaemia showed increased values of Total Cholesterol, Triglycerides, LDL-c, Castelli Index I and II and estimative of LDL-c size particle and decreased HDL-c (High Density Lipoprotein) values. The comparison between hs-CRP levels and biochemical parameters shows significant differences for Body Mass Index, Triglycerides, HDL-c and the estimative of LDL-c particle. Also, the presence of Metabolic Syndrome is more prevalent in patients with high levels of hs-CRP. Diabetes patients have more significant increase in morbidity and mortality than the general population frequently due to further complications associated with the resistance to insulin. It is indispensable to outline the anthropometric and biochemical profile from hyperglycemic patients in order to work on secondary prevention of cardiovascular disease.