TITLE:
Biotoxicity of CdS/CdSe Core-Shell Nano-Structures
AUTHORS:
Sreenu Bhanoth, Anuraj S. Kshirsagar, Pawan K. Khanna, Aakriti Tyagi, Anita K. Verma
KEYWORDS:
Quantum Dots, Metal Chalcogenides, Bio-Toxicity, Cell Lines
JOURNAL NAME:
Advances in Nanoparticles,
Vol.5 No.1,
February
4,
2016
ABSTRACT: The cytotoxicity of hydrophobic QDs CdS/CdSe was tested assigning MTT assay on Human Embryonic Kidney cells (HEK-293), breast cancer cells (MCF-7) and Enrichlish Ascitices Cells (EAC). Approximately 65% bio-toxicity was observed in MCF-7 for the core-shell QDs. These QDs may also find effective applications in other optoelectronic devices. CdS/CdSe core-shell hetrostructure quantum dots (QDs) were generated by chemical reaction between the respective chalcogens and cadmium metal salt. Sulphur powder was utilized for CdS core preparation while selenium was extracted from an organoselenium compound to impart CdSe shell layer at a temperature between 150℃ - 200℃. So-prepared core-shell QDs showed good optical properties. The particle size was found to be in the range of 3 - 4 nm with spherical morphology and cubic crystal structure.