TITLE:
Thyroid Hormone Levels and Its Relationship with Human Chorionic Gonadotropin in Patients with Hydatidiform Mole
AUTHORS:
Nankali Anisodowleh, Keshavarzi Farahnaz, Jalilian Nasrin, Hematti Maryam, Basami Elaheh
KEYWORDS:
Molar Pregnancy, TSH, BHCG, T3, T4, Hyperthyroidism
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.6 No.1,
January
25,
2016
ABSTRACT: Objective: Hydatidiform pregnancy occurs in 1:1000 pregnancies worldwide;
incidence is higher in Asian countries. In approximately 5% of cases of hydatidiform
mole, clinical hyperthyroidism is present. The aim of this study was to examine
the relation between HCG level and thyroid function test. Methods: During 5
years (2009-2013) we included 146 cases of molar pregnancies into the study at
Imam Reza teaching hospital. The demographic and clinical data as well as serum
initial HCG level and thyroid function test (TSH T3 T4) were retrieved and
entered into prepared proformas. p In this study significantly inverse relation was
observed between B-HCG and TSH (p = 0.05). We also found a significantly direct
correlation between B-HCG and T3 (p = 0.01) and T4 (p = 0.01). Conclusion: We
concluded significantly meaningful relationship between BHCG and T3, T4, TSH.