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Malouf, G.G., Camparo, P., Oudard, S., Schleiermacher, G., Theodore, C., Rustine, A., Dutcher, J., Billemont, B., Rixe, O., Bompas, E., Guillot, A., Boccon-Gibod, L., Couturier, J., Molinie, V. and Escudier, B. (2010) Targeted Agents in Metastatic Xp11 Translocation/TFE3 Gene Fusion Renal Cell Carcinoma (RCC): A Report from the Juvenile RCC Network. Annals of Oncology, 21, 1834-1838.
http://dx.doi.org/10.1093/annonc/mdq029

has been cited by the following article:

• TITLE: Renal Cell Carcinoma Associated with Xp11.2 Translocation/TFE3 Gene Fusion: A Case Report with Immunohistochemical and Cytological Features

  AUTHORS: Takuji Tanaka, Kuniaki Hirai, Fumimasa Etori, Masashi Matsuyama, Naoki Watanabe, Hiromi Kondo, Masayoshi Tamaki, Tatsuya Yamashita, Shiho Yasue, Mika Noda, Kunihiro Shinoda, Hisao Komeda

  KEYWORDS: Renal Cell Carcinoma, Xp11.2 Translocation, TFE3, Cytology, Immunohistochemistry, Immunocytochemistry

  JOURNAL NAME: Open Journal of Pathology, Vol.6 No.1, January 22, 2016

  ABSTRACT: Gene fusions involving two of the MiT subfamily factors, such as TFE3, TFEB, TFC and MiTF, have been identified in renal cell carcinoma (RCC). Xp11.2 translocation RCC is a rare pediatric neoplasm that harbors gene fusions involving TFE3, which plays an important role in cell proliferation and survival. We herein present a case of RCC associated with Xp11.2 translocation/TFE3 gene fusion in a 14-year-old Japanese boy presenting gross hematuria and body weight loss. The tumor was characterized by histopathology, cytology and TFE3-immunohistochemistry/immunocytochemistry. Knowledge of distinctive morphological and immunostaining features of this tumor can help to accurately diagnose this rare subset of translocation associated RCC in routine pathological diagnostic procedures.