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Argani, P. and Ladanyi, M. (2004) Renal Carcinomas Associated with Xp11. 2 Translocations/TFE3 Gene Fusions. In: Eble, J.N., Sauter, G., Epstein, J.I. and Sesterhenn, I.A., Eds., World Health Organization Classification of Tumours, IARC Press, Lyon, 37-38.

has been cited by the following article:

• TITLE: Renal Cell Carcinoma Associated with Xp11.2 Translocation/TFE3 Gene Fusion: A Case Report with Immunohistochemical and Cytological Features

  AUTHORS: Takuji Tanaka, Kuniaki Hirai, Fumimasa Etori, Masashi Matsuyama, Naoki Watanabe, Hiromi Kondo, Masayoshi Tamaki, Tatsuya Yamashita, Shiho Yasue, Mika Noda, Kunihiro Shinoda, Hisao Komeda

  KEYWORDS: Renal Cell Carcinoma, Xp11.2 Translocation, TFE3, Cytology, Immunohistochemistry, Immunocytochemistry

  JOURNAL NAME: Open Journal of Pathology, Vol.6 No.1, January 22, 2016

  ABSTRACT: Gene fusions involving two of the MiT subfamily factors, such as TFE3, TFEB, TFC and MiTF, have been identified in renal cell carcinoma (RCC). Xp11.2 translocation RCC is a rare pediatric neoplasm that harbors gene fusions involving TFE3, which plays an important role in cell proliferation and survival. We herein present a case of RCC associated with Xp11.2 translocation/TFE3 gene fusion in a 14-year-old Japanese boy presenting gross hematuria and body weight loss. The tumor was characterized by histopathology, cytology and TFE3-immunohistochemistry/immunocytochemistry. Knowledge of distinctive morphological and immunostaining features of this tumor can help to accurately diagnose this rare subset of translocation associated RCC in routine pathological diagnostic procedures.