TITLE:
Tubal Infertility and Chlamydia Trachomatis in a Congolese Infertile Population
AUTHORS:
E. Mboloko, M. Fataki, E. Nzau-Ngoma, L. D. Lokengo, A. Ingala, B. C. J. Bikuelo, A. N. Apangwa, M. M. M. Kapend, M. Mboloko, N. Mumba
KEYWORDS:
Tubal Infertility, Chlamydia Trachomatis, Chlamydia Trachomatis Antibody Titer Test, Sub-Saharan Area
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.6 No.1,
January
21,
2016
ABSTRACT: Infertility of tubal origin is the most frequent in
sub-Saharan area. It is due to tuboperitoneal lesions mainly because of
infection; especially sexually transmitted infection. Worldwide, Chlamydia
trachomatis is the main pathogen. In our setting, some studies failed to
establish the link between tubal infertility and chlamydia trachomatis. The
current study aimed to determine the local data related to chlamydia
trachomatis role in tubal infertility and the usefulness of Chlamydia
trachomatis antibody titer test (CAT) in discrimination of the patients with
and without tuboperitoneal lesions. Patients’ average age was 33.9 ± 4.8 years,
average coitarche 19.4 ± 4.4 years and average number of partners: 3.1 ± 1.6.
The level of CAT is correlated to the tuboperitoneal severity. CAT was more
specific (93.3%; CI 95%: 81.7 - 98.6) than sensitive (72.7% CI 95%: 49.8 -
89.3) and discriminated correctly 89% (AUC = 0.89) of the patients with or
without tuboperitoneal lesions. In conclusion, as it is stated worldwide,
Chlamydia trachomatis is the most frequent sexually transmitted pathogen
associated with tubal infertility. CAT has to be used as a tool to select
patients to be submitted to invasive investigation, like laparoscopy.