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D. J. Brown, “Pyrimidines and their Benzo Derivatives, in Comprehensive Heterocyclic Chemistry,” (Eds. A. R. Katritzky and C. W. Rees), Pergamon Press, Oxford, 1984.

has been cited by the following article:

• TITLE: Synthesis, Spectroscopy and X-Ray Crystal Structure of 9-Methyl-3-Thiophen-2-Yl-Thieno [3, 2-e] [1, 2, 4] Triazolo [4, 3-c] Pyrimidine-8-Carboxylic Acid Ethyl Ester

  AUTHORS: Nikhath Fathima, Mohamed Ziaulla, Afshan Banu, Shridhar Ishwar Panchamukhi, Imtiyaz Ahmed Khazi, Noor Shahina Begum

  KEYWORDS: Thieno-Triazolo-Pyrimidine Derivative, Characterization, X-Ray Crystallographic Analysis, C-H…N, C-H…O and π-π Weak Interactions

  JOURNAL NAME: American Journal of Analytical Chemistry, Vol.2 No.3, July 26, 2011

  ABSTRACT: The Preparation of 9-Methyl-3-thiophen-2-yl-thieno [3, 2-e] [1, 2, 4] triazolo [4, 3-c] pyrimi-dine-8-carboxylic acid ethyl ester is described. Elemental analysis, IR spectrum, 1H NMR, 13C NMR and X-ray crystal structure analyses were carried out to determine the composition and molecular structure of the title compound. There are two independent molecules in the asymmetric unit exhibiting intermolecular C-H…N, C-H…O interactions with additional π-π interaction that further helps in stabilizing the supramolecular structure. The results showed that the proposed method for synthesis is simple, precise and accurate which was further confirmed by crystal structure analysis.