TITLE:
Prevalence of Low Levels of Vitamin D in Type 2 Diabetes at the City of Mangueirinha, Paraná, Southern Brazil
AUTHORS:
Paulo Sérgio Chiamolera, Cristiano Alvariza Amaral, Monica Cristina de Oliveira Russo, Gilberto de Oliveira Netto, Ricardo Augusto Fernandes, Ricardo Teles de Andrade, José Luiz Gonçalves Buscariolli, Denise Rosso Tenório Wanderley Rocha, Alberto Krayyem Arbex
KEYWORDS:
25 OH Vitamin D, Type 2 Diabetes Mellitus, Cardiovascular Risk
JOURNAL NAME:
Open Journal of Endocrine and Metabolic Diseases,
Vol.6 No.1,
January
14,
2016
ABSTRACT: Background: Diabetes
mellitus is a worldwide epidemic. In 2002 there were 173 million diabetic
adults worldwide, and these numbers are expected to reach up to 300 million
people by 2030. Meanwhile, vitamin D deficiency has its worldwide prevalence
directly influenced by factors as solar radiation, skin color, latitude and
seasons, cultural habits of populations such as clothing and food, and these
factors are important to explain the different prevalences of vitamin D
deficiency in the world. Methods: A prospective cross-sectional cohort study
was conducted with patients in the outpatient clinic of the Health Unit of the
city of Mangueirinha, Paraná, Southern Brazil. Fifty-four type 2 diabetic
patients were evaluated (38 women and 16 men), aged 55.8 ± 12.6 years. The
following variables were evaluated: age, ethnicity, presence of type 2 diabetes
(DM2), hypertension, dyslipidemia, weight, BMI, WC, blood pressure, blood
glucose, glycated hemoglobin, ionized calcium, PTH, 25-OH Vit, total
cholesterol, HDL, LDL, urea, creatinine, uric acid and red cell/hematocrit.
Results: mean BMI was 30.2 ± 4.4 kg/m2, indicating class 1 obesity
in this population. Fasting glucose levels were approximately 169.8 ± 74.5
mg/dL. The 25-OH vitamin D values for this population were 23.4 ± 8.3 ng/mL,
and 13% of them showed 25-OH vitamin D levels above 30 mg/dL. Fifty percent of
those patients had vitamin D levels lower than 30 mg/dL, and 37% had less than
20 mg/dL. Conclusions: this study suggests that vitamin D is associated with
low levels of vitamin D in type 2 diabetic patients. Supplementation of vitamin
D should be considered in diabetic patients, when levels under 30 mg/mL are
found.