TITLE:
Retroperitoneal Extraskeletal Osteosarcoma in a Pregnant Woman Incidentally Found on Cesarean Section
AUTHORS:
Shizue Fujihara, Teruyuki Yamasaki, Kontoku Shimokawa, Han-Seung Yoon
KEYWORDS:
Extraskeletal Osteosarcoma, Pregnant Woman, MDM2, CDK4
JOURNAL NAME:
Open Journal of Pathology,
Vol.6 No.1,
January
11,
2016
ABSTRACT: Extraskeletal osteosarcoma (ESO) is a rare
malignant mesenchymal neoplasm accounting for 1% - 2% of all soft tissue
sarcomas that produce osteoid, bone, and/or chondroid material. Here we report
the first case of a retroperitoneal ESO in a 35-year-old pregnant woman. A
retroperitoneal ESO was incidentally found at cesarean section. Despite
treatment, she rapidly died from wide spread dissemination. We focus on
histological characteristics including immunohistochemical results and
differential diagnosis of ESO.