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Ryan, J.G. (1998) Hemoglobin Toxsins. In: Viccellio, P., Bania, T., Bernt, J., Hoffman, R.S., Kulig, K.W., Mofenson, H.C., Osborn, H.H., Wang, R.Y., Wax, P.M., Eds., Emergency Toxsicology, Lippincott-Raven, New York, 227-238.

has been cited by the following article:

• TITLE: An Attempt on Methemoglobinemia: It’s Treatment and Relationship between Treatment and Cerebral Oximeter Value: Case Presentation

  AUTHORS: İlknur S. Şeker, Onur Özlü, Yavuz Demiraran, Gülbin Sezen, Ertay Boran

  KEYWORDS: Methemoglobinemia, Anesthesiology, Cerebral Oximeter, Pulse Oximeter

  JOURNAL NAME: International Journal of Clinical Medicine, Vol.6 No.12, December 29, 2015

  ABSTRACT: Background: Our paper aimed to investigate whether there was a correlation among the pulse oximetry, cerebral oximetry (CO) and MetHb (methemoglobin) values of a patient with congenital methemoglobinemia who underwent a laparoscopic cholecystectomy operation. Case: The 35-year-old male patient with a weight of 70 kg, body massindex (BMI) of 21, American Society of Anesthesia status-2(ASA-2) category who was planned for laparoscopic cholecystectomy operation was identified to have been diagnosed with congenital methemoglobinemia as per his medical history was methemoglobin levels ranged between 12% and 20% according to the periodical measurements taken for the past 3 years. The patient received standard monitoring during anesthesia and device monitoring with a cerebral oximeter (Invos 5100C somatic/cerebral oximeter, Covidien) and a CO-oximetry (Rad ?87 “Rainbow”, Masimo Inc., Irvine, CA) device to continuously follow up his MetHb values was also added. During the intra-operative follow-up, the patient’s methemoglobin level rose to 16%, his peripheral oxygen saturation levels decreased to 86% and his cerebral oximetry values were identified to have also decreased; therefore, methylene blue (MB) was intravenously administered to the patient. The patient continued to be followed up in the post-operative period and he did not develop any complications. Discussion: Appropriate treatment and monitoring enabled the prevention of potential complications. We believe that monitoring with NIRS and MASIMO CO-oximetry device will enable physicians to perform a safe follow-up and treatment in the intraoperative and postoperative follow-up of methemoglobinemia patients.