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Kim, J.S., Gatto, B., Yu, C., Liu, A., Liu, L.F. and La Voie, E.J. (1996) Substituted 2,5’-Bi-1H-benzimidazoles:? Topoisomerase I Inhibition and Cytotoxicity. Journal of Medicinal Chemistry, 39, 992-998.
http://dx.doi.org/10.1021/jm950412w

has been cited by the following article:

• TITLE: Green and High Efficient Synthesis of 2-Aryl Benzimidazoles: Reaction of Arylidene Malononitrile and 1,2-Phenylenediamine Derivatives in Water or Solvent-Free Conditions

  AUTHORS: Azizollah Habibi, Yousef Valizadeh, Marjan Mollazadeh, Abdolali Alizadeh

  KEYWORDS: Benzimidazoles, Green Chemistry, Arylidene Malononitrile, 1, 2-Phenylenediamines

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.5 No.4, December 9, 2015

  ABSTRACT: A fast, high efficiency and environmentally friendly procedure for the synthesis of 2-aryl benzim-idazole derivatives has been reported. Reaction between 1,2-phenylenediamine derivatives and arylidene malononitrile under aqueous media and also solvent-free conditions generates 2-aryl benzimidazole derivatives with a high yield.