TITLE:
Correlation between Asymptomatic Bacteriuria and HIV-1 Viral Load Level and CD4 Count in Pregnant Women on Antiretroviral Therapy in N’djamena (Chad)
AUTHORS:
Adoum Fouda Abderrazzack, Mounerou Salou, Akouda Patassi, Degninou Yehadji, Yaovi Ameyapoh
KEYWORDS:
Pregnant Women, Asymptomatic Bacteriuria, Lymphocyte CD4, Viral Load
JOURNAL NAME:
World Journal of AIDS,
Vol.5 No.4,
December
8,
2015
ABSTRACT: A cross-sectional study was conducted at
the “Centre de l’Appui Psycho-Médico-Social (APMS)” which is a centre for
Psychological and Medical Support in N'Djamena (Chad) from January to March
2014. The aim of this study was to evaluate the correlation between
asymptomatic bacteriuria (ASB) and viral load level and CD4 count in
seventy-six (76) HIV-1 infected pregnant women on antiretroviral therapy (ART).
Urine culture and bacteria identification were performed by using a chromogenic
culture medium (UriselectR4). T CD4+ lymphocytes count and viral load
measurement were done respectively on PIMATM test and Abbott m2000 RealTime
HIV-1. In this study, 25 (32.9%) pregnant women were carrying ASB and major
bacteria; Escherichia coli and Streptococcus agalactiae known to cause neonatal
meningitis to newborns were identified. Bacteria were isolated mainly in women
with CD4 lymphocytes
3log (70%) (19/25). Besides the prevention of mother to child transmission of
HIV, which remains a goal, it is important to prevent also the transmission of
other microorganisms causing neonatal infections. Our findings support the
needs to do bacteriological analysis of urine in every HIV-infected pregnant
woman at least in late pregnancy.