TITLE:
Research on the Repeated Sequences among tRNA Sequences
AUTHORS:
Fangping Wei, Yuanze Mao, Zhenxiong Lan
KEYWORDS:
tRNA Sequences, Repeated Sequences, Anticodons
JOURNAL NAME:
Advances in Bioscience and Biotechnology,
Vol.6 No.11,
November
25,
2015
ABSTRACT: Many theories thought that present-day tRNA sequences evolved from some short RNA hairpins
which contain a simple stem-loop structure. To find out these significant fragment sequences, the
repeated sequences of different length within 3420 tRNA sequences are counted and analyzed.
The results show that: 1) the probability of occurrence P(i) with the given repeated sequences i
follows a power-law distribution when the length K of repeated sequences is longer than four
bases, and in this case, the total number N(n) of occurrence with the repeated times n follows a
power-law distribution too; 2) the sequence of the length K which repeats the largest times is just
only sequence of the length K-b wobbling b bases on its left or right side (b varies between 1 and
K-1); 3) the same repeated sequences are found nearly at the identical site in different tRNA
sequences as the length K of repeated sequences is longer than five bases. Then a hypothesis of the
origin and evolution mechanisms of tRNA sequences is proposed and discussed.