TITLE:
Correlations of Body Mass Index, Japan-Defined and IDF-Defined Waist Circumference, Visceral and Subcutaneous Fat Area with Metabolic Parameters in Japanese Patients with Type 2 Diabetes
AUTHORS:
Hidekatsu Yanai, Yuji Hirowatari
KEYWORDS:
Body Mass Index, Type 2 Diabetes, Visceral Fat Area, Waist Circumference
JOURNAL NAME:
Journal of Diabetes Mellitus,
Vol.5 No.4,
November
6,
2015
ABSTRACT: Obesity is included in the definition of metabolic syndrome. However,
there are many controversies surrounding the evaluation of obesity such as body
mass index (BMI) and waist circumference (WC) in the definition of metabolic
syndrome among various populations. To understand precisely how various
anthropometric indices of obesity influence metabolic parameters, we studied
the correlations of BMI, WC (Japanese criteria), WC (IDF criteria), visceral
fat area (VFA), subcutaneous fat area (SFA) and the VFA/SFA ratio with
metabolic parameters in patients with type 2 diabetes. The influences of BMI
and WC on diastolic blood pressure and HDL-cholesterol were larger than VFA,
whereas the influences of visceral fat area on triglyceride, very low-density
lipoprotein-cholesterol, C-peptide and high-sensitivity C-reactive protein were
larger than BMI and WC. WC (IDF) was the strongest determinant of adiponectin
among anthropometric indices. Present study showed significant different
associations of BMI, Japan- and IDF-defined WC, VFA, SFA and the VFA/SFA ratio
with blood pressure, glucose and lipid metabolism, and adipocytokines in Japanese
patients with type 2 diabetes.