TITLE:
Carcinoembryonic Antigen as a Prognostic Factor in Colorectal Cancer with Liver Metastases
AUTHORS:
George E. McNally, David M. Lloyd, Jorge P. Grondona
KEYWORDS:
Carcinoembryonic Antigen (CEA), Colorectal Cancer Survival, Liver Metastasis, Postoperative Mortality
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.6 No.12,
November
5,
2015
ABSTRACT: Aim: The objective of this study was to investigate
the prognostic value of serum carcinoembryonic antigen (CEA) level in
colorectal cancer patients with liver metastases. The serum CEA level was
recorded at the point of metastasis diagnosis, differing from the majority of
literature looking at preoperative metastasectomy CEA level. Methods: From
January 2010 to December 2014, 138 patients with a diagnosis of colorectal
cancer and liver metastases were included in the study—population from Buenos Aires, Argentina. Patients with both
resectable and unresectable liver metastases were followed up over a 4-year
period. Kaplan Meier survival analysis was used to produce survival curves that
were compared by log-rank test. Results: The overall survival for all patients
studied with a CEA