TITLE:
The Efficacy of Tocilizumab for Takayasu Arteritis: Review of the Literatures
AUTHORS:
Nesibe Karahan Yeşil, Hatice Şahin, Metin Işik, Ziyaeddin Aktop, İsmail Doğan, Ali Erdem Baki
KEYWORDS:
Takayasu Arteritis, Tocilizumab, Corticosteroid
JOURNAL NAME:
Open Journal of Rheumatology and Autoimmune Diseases,
Vol.5 No.4,
November
2,
2015
ABSTRACT: Takayasu arteritis is a large vessel vasculitis of the young women with giant cells and granuloma formation. The diagnosis and management of the disease are really not so easy because of the insidious onset and the difficulties in assessment of disease activity. Nearly 60% of the patients are corticosteroid resistant or dependent and relapses are very frequent during taper of the dose [1]. The novel biologic agents as Anti-TNF, Rutiximab and Tocilizumab provide acceptable response rates with low toxicity. Herein, we reviewed the efficacy of Tocilizumab in Takayasu arteritis.