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Choi, Y.E. and Park, E. (2015) Ferulic Acid in Combination with PARP Inhibitor Sensitizes Breastcancer Cells as Chemotherapeutic Strategy. Biochemical and Biophysical Research Communications, 458, e520-e524.

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• TITLE: Synthesis, Characterization and Biological Screening of Ferulic Acid Derivatives

  AUTHORS: T. Naga Ravi Kiran, Ch. Sri Alekhya, B. V. S. Lokesh, A. V. S. Madhu Latha, Y. Rajendra Prasad, T. Naga Mounika

  KEYWORDS: Ferulic Acid, Cytotoxicity, Hela (Cervical Cancer Cell Lines), A549 (Lung Cancer Cell Lines), HT-29 (Colorectal Cancer Cell Lines), Synthesis

  JOURNAL NAME: Journal of Cancer Therapy, Vol.6 No.10, September 24, 2015

  ABSTRACT: According to WHO, cancer is a leading cause of death worldwide, accounting for 8.2 million deaths in 2012. Among several factors involved in the pathogenesis of cancer, free radical formation followed by damage to DNA and cell protein is one of the causes. Natural plant products have gained enormous interest in the prevention or treatment of chronic diseases. Ferulic acid, like other phenolic acids (caffeic acid, sinapic acid) possess anti cancer activity. A series of ferulic esters (FE1 - FE11) and ferulic amides (FA1 - FA10) were synthesized and evaluated for their cytotoxic activity.