TITLE:
Screenning of Chlamydia trachomatis Infection among Women Attending Outpatient Clinic of Infertility
AUTHORS:
Heloisa Lopes Lavorato, Natália Prearo Moço, Laura Fernandes Martin, Ana Gabriela Pontes Santos, Anaglória Pontes, Marli Teresinha Cassamassimo Duarte, Márcia Guimarães da Silva
KEYWORDS:
Chlamydial Infection, Infertility, Molecular Diagnosis
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.5 No.11,
September
18,
2015
ABSTRACT: Objective: The goal of this study was to determine the prevalence of C.
trachomatis in women diagnosed with infertility attending the Outpatient
Clinic of Infertility from Botucatu Medical School, UNESP, Brazil. Patients and
Methods: This molecular study enrolled a total of 112 women. Among these
patients, 62 presented primary infertility while 50 presented secondary
infertility. The criteria for eligibility included women who were:
reproductive-aged; no prior report of seroconversion for HIV; no antibiotic or
vaginal cream used in the preceding 30 days; and abstinence from sexual
intercourse for 72 hours before the visit. The women were submitted to a gynecological
examination and cervical samples were collected with an endocervical cytobrush
for molecular analysis of C. trachomatis. Results: The prevalence of
chlamydial infection was 8% with similar prevalence between primary (8.1%) and
secondary (8.0%) infertility. Conclusion: Considering the asymptomatic nature
of chlamydial infection and its association with tubal factor infertility,
there is a pressing need to incorporate the screening of C. trachomatis infection as part of the routine investigation for infertility. The early
diagnostic by screening can minimize complications and reduce Public Health
costs with Assisted Reproductive Technology.