TITLE:
Prevalence and Risk Factors of Hepatitis B and Hepatitis C Virus Infections among Patients with Chronic Renal Failure in Zabeed City, Yemen Republic
AUTHORS:
Mohammed A. Al-Hegami, Abdullah Al-Mamari, Abdulrahman S. Al-Kadasse, Fadhl A. S. Al-Gasha’a, Sadeq Al-Hag, Adel A. S. Al-Hegami
KEYWORDS:
HBV, HCV, Hemodialysis, Zabeed City, Yemen Republic
JOURNAL NAME:
Open Journal of Medical Microbiology,
Vol.5 No.3,
September
18,
2015
ABSTRACT: Background and Aims: Patients on hemodialysis (HD) are at high risk of viral hepatitis due to high number of blood transfusion sessions, prolonged vascular access, high exposure to infected patients and contaminated equipment, or cross contamination from the dialysis circuits and pose problems in the management of patients in the renal dialysis units. This study was done to determine the prevalence of Hepatitis B virus (HBV) & Hepatitis C virus (HCV), in patients on hemodialysis in Zabeed City, Yemen Republic, and address the major risk factors for transmission of these viruses among HD patients. Materials and Methods: In this cross-sectional study, during June, 2013 to October, 2014, a total of 243 chronic hemodialysis patients were tested. Patients were selected from many regions by cluster sampling from Zabeed public hospital, (hemodialysis center) in Zabeed City, Yemen Republic. A close ended and multiple choice-based questionnaires were completed and HBsAg and anti-HCV antibodies were assessed using third generation enzyme linked immunoassay kit as serological testing and data were analyzed using the SPSS-20 software. Results: The overall prevalence of positive HBsAg was (48.83%) while positive anti-HCV was (46.01%) and (5.16%) mixed infection with HBV and HCV. Analysis of risk factors in patients with HBV & HCV infection is showed the history of blood transfusion and duration of hemodialysis was found to be a statistically significant (P