TITLE:
A Microarray Analysis of Parkinson’s Disease: New Clues and Evaluation
AUTHORS:
Lirong Huo, Xibin Liang, Yi He, Xiaomin Wang
KEYWORDS:
Parkinson’s Disease, 6-OHDA, Microarray, Discrete Genes, Cortex, Striatum
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.3 No.9,
September
17,
2015
ABSTRACT: Parkinson’s disease (PD) is complex and
most likely results from an unknown combination of genetic and environmental
factors. Here, we defined discrete genes (DGs) in a microarray analysis and found
that the percentage of DGs versus all analyzable genes correlated with PD
progression. Furthermore, this new parameter was also easily used to evaluate
the therapeutic effect of high- frequency electro-acupuncture (EA), thus
improving symptoms of PD model rats.