TITLE:
A Simple Procedure for Termination of Pregnancy in the Late First Trimester with Mifeprostone and Misoprostol
AUTHORS:
Heini Joensuu-Manninen, Ritva Nissi, Markku Santala, Anne Talvensaari-Mattila
KEYWORDS:
Medical Termination of Pregnancy, Late First Trimester, Safe Abortion, Mifepristone, Misoprostol
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.5 No.11,
September
14,
2015
ABSTRACT: Purpose: To assess the efficacy of
medical methods for termination of pregnancy at 9 - 12 weeks of gestation.
Methods: Between December 2008 and December 2010, the 116 consecutive women
received 200 mg oral mifepristone and after 24 - 36 hours they applied 800 μg
vaginal misoprostol to medically terminate pregnancy. If the products of
conception did not pass, three further doses of 400 μg misoprostol were given
vaginally at three hours intervals to medically terminate pregnancy. Results:
Of the 116 patients undergoing the procedure 104 (90%) aborted completely. Half
of the patients aborted within 6 hours. After medical termination, five per cent
of the women were treated because of infection, and five per cent needed a
revisit to hospital because of excessive bleeding. Two women received a blood
transfusion. Previous live births or previous inducted abortion is presented in
the study results. Conclusions: Medical
abortion at 9 - 12 weeks’ gestation is a safe alternative to surgery.