TITLE:
The Use of Human Amniotic Allograft on Osteochondritis Dissecans of the Talar Dome: A Comparison with and without Allografts in Arthroscopically Treated Ankles
AUTHORS:
J. Joseph Anderson, Zflan Swayzee
KEYWORDS:
Bone Lesions, Human Amniotic Allograft, Ankle Arthroscopy, Talus Fractures, Stem Cells, Cartilage Restoration
JOURNAL NAME:
Surgical Science,
Vol.6 No.9,
September
8,
2015
ABSTRACT: Arthroscopy of the ankle with micro-fracture technique is one way to
initially treat symptomatic talar dome lesions. Human amniotic allograft has
been used in similar bone, soft tissue and cartilage defects to aid in healing
of tissue using graft cells that have not differentiated into a particular cell
line. Patients were taken from the primary surgeon’s practice to include those
who had undergone arthroscopy with micro-fracture technique for treatment of a
talar dome lesion less than 2 cm2. 101 patient surgeries were
completed arthroscopically without additional major procedures. 54 surgeries
were completed with human amniotic allograft; 47 were completed without
(control group). Modified ACFAS ankle scores were taken pre-operatively, 3, 12
and 24 months post-operatively. Visual analog pain scores were taken pre-operatively
and 24 months post-operatively. Results comparing pre-operative modified ACFAS
scores between the control and graft groups were not significantly different (p
= 0.14). There was a significant improvement in both groups’ scores following
ankle arthroscopy with micro-fracture as expected. However, the amniotic tissue
group did significantly better when comparing the post-operative scores between
the control and graft group. Pain scores comparing control and amniotic patient
groups were significant (p 2,
significantly improves the patients’ pain and ACFAS scores.