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P.R Fox, M.A Oyama, C. Reynolds, J.E Rush, T.C Defrancesco, B.W Keene, C.E Atkins, K.A Macdonald , K. ESchober , J.D Bonagura , R.L Stepien , H.B Kellihan, T.P Nguyenba, L.B Lehmkuhl, B.K Lefbom, N.S Moise , D.F Hogan, “Utility of plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) to distinguish between congestive heart failure and non-cardiac causes of acute dyspnea in cats”, J Vet Cardiol., Vol. 11, Suppl 1, 2009, pp S51-61
has been cited by the following article:
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TITLE:
N-Terminal Pro-BNP in Acute Coronary Syndrome Patients with ST Elevation versus Non ST Elevation Myocardial Infarction
AUTHORS:
Ragaa H. M Salama, Alaa E. A El- Moniem, Nour El-Hefney, Tarek Samor
KEYWORDS:
NT-proPNB, Acute Coronary Syndrome, ST Segment, Cardiac Markers
JOURNAL NAME:
International Journal of Clinical Medicine,
Vol.2 No.3,
July
19,
2011
ABSTRACT: The study aimed to evaluate the differences in secretion of NT-proBNP and conventional cardiac markers in patients with STE-ACS vs NSTE-ACS as a trial to solve the dilemma of the early detection of myocardial ischemia in NSTE-ACS. Sixty two patients with acute coronary syndrome (ACS) divided into 2 groups according to ECG: group1 with elevated ST segment in ECG (STE-ACS) and group 2 with non elevated ST segment (NSTE-ACS).Twenty healthy subjects with matched age and sex were enrolled as control group in this study. In the sera of all subjects, levels of NT –proBNP, CK-MB and troponin-T were measured by different kits. CK-MB and TnT were both significantly higher in STE-ACS patients compared to NSTE-ACS patients. Conversely, NT-proBNP was significantly higher in NSTE-ACS patients than STE-ACS especially within 4 hours from onset of chest pain. Comparison between NT-proBNP, TnT and CK-MB levels by ROC curves revealed area under the curves = 0.68, 0.31, 0.17 respectively. NT-proBNP at cutoff 415 pg/mL in NSTE-ACS patients had higher sensitivity and specificity (92%, 39%; respectively) than other markers that will help in earl diagnosis of NSTE-ACS.