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Qureshi, A.A., Qureshi, N., Wright, J.J.K., Shen, Z., Kramer, G., Gapor, A., Chong, Y.H., DeWitt, G., Ong, A.S.H., Peterson, D.M. and Bradlow, B.A. (1991) Lowering of Serum-Cholesterol in Hypercholesterolemic Humans by Tocotrienols (Palmvitee). The American Journal of Clinical Nutrition, 53, S1021-S1026.

has been cited by the following article:

• TITLE: Effects of Tocols Rich Fraction Isolated from Rice Bran Oil Deodorizer Distillate on Plasma and Hepatic Lipid Concentrations in Rats

  AUTHORS: Tina A. Gomes, Xuan Gu, Cindi R. Brownmiller, Luke Howard, Cesar M. Compadre, Sun-Ok Lee

  KEYWORDS: Rice Bran Oil Deodorizer Distillate, Tocols, Oral Gavage, Triglycerides

  JOURNAL NAME: Journal of Biosciences and Medicines, Vol.3 No.9, September 7, 2015

  ABSTRACT: A great deal of attention has been focused on the potential health benefits of using rice bran oil because it is a rich source of bioactive compounds. Rice bran oil deodorizer distillate (RBODD) is a byproduct obtained from distillation of rice bran oil. Elevated plasma cholesterol level is one of the major risk factors for coronary heart disease. The objective of this study was to investigate the effects of tocols (tocopherols + tocotrienols) rich fraction isolated from RBODD on plasma and liver lipid concentrations in rats. Male Sprague Dawley rats (6 weeks of age) were randomly assigned into three groups: normal fat control (NFC), high fat control (HFC) and high fat diet plus tocols rich fraction (RBODD). RBODD was administered daily for 3 weeks by oral gavage using 5% of Tween-80 as a vehicle. The rats in the control groups received 5% of Tween-80 alone in the same manner. Blood samples and livers were collected at the end of the feeding period. RBODD group had significantly lower plasma triglyceride levels compared to the HFC group (p