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Schinner S, Willenberg HS, Krause D, Schott M, Lamounier-Zepter V, Krug AW, Ehrhart-Bornstein M, Bornstein M, Bornstein SR, and Scherbaum WA. Adipocyte-derived products include the transcription of the StAR promoter and stimulate aldosterone and cortisol secretion from adrenocortical cells through the Wnt-signaling pathway. Int J Obes. Vol. 31, No. 5, 2007, pp. 864-870.

has been cited by the following article:

• TITLE: Coexistence of the Hypersecretion of Catecholamine, Adrenal Cortical Nodular Hyperplasia, and Nephrotic-Range Proteinuria of Focal Segmental Scleronephrosis: Is It Fat-Induced Hypertension?

  AUTHORS: Khanh Vinh Quốc Luong, Lan Thị Hòang Nguyễn, Sĩ Văn Nguyễn, Ninh T Nguyễn

  KEYWORDS: Pheochromocytoma, Aldosteronism, Adipocyte, Nephrotic Syndrome, Focal Segmental Scleronephrosis, Adrenal Cortical Hyperplasia

  JOURNAL NAME: International Journal of Clinical Medicine, Vol.2 No.3, July 19, 2011

  ABSTRACT: Two patients had a long history of hypertension and one of them also had a nephrotic-range proteinuria secondary to focal segmental scleronephrosis which had been diagnosed by kidney biopsy. They presented with uncontrolled hypertension. Laboratory examination suggested hypersecretion of catecholamines by the left adrenal glands in both patients and primary aldosteronism in one of them. A computed tomography scan revealed small nodules on left adrenal gland in both patients. Patients underwent laparoscopic left adrenalectomy. After surgery, blood pressure was normalized and proteinuria was resolved. Most interestingly, prominent adipocytes infiltrated were detected in the adrenal cortex and were associated with the presence of lymphocytes, which suggested that adipocytes might have a role in the pathogenesis of these diseases in our patients.