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Ani, O.I. (2015) Surface Energetics Study of the Interactions between HIV and Blood Cells Treated with Antiretroviral Drugs. Ph.D. Dissertation, Nnamdi Azikiwe University, Awka.

has been cited by the following article:

• TITLE: The Effects of Antiretroviral Drugs on the Absorbance Characteristics of HIV-Infected Blood

  AUTHORS: Okwuchukwu Ani, Sam Omenyi, Chinonso Achebe

  KEYWORDS: Absorbance, Transmittance, Dielectric Constant, Human Immunodeficiency Virus, Antiretroviral Drug, Coating Effectiveness, Lymphocyte, Wavelength

  JOURNAL NAME: Journal of Biomedical Science and Engineering, Vol.8 No.9, September 4, 2015

  ABSTRACT: In the twenty first century research works, there may be a need to achieve a more reliable research result through a synergy between engineers and biological researchers. The peak absorbance data for various interacting systems were measured. These were used to show that the antiretroviral drug has the effect of increasing the peak absorbance values of both the uninfected and infected blood components, i.e., the drugs are made able to increase the light absorption capacity of the blood cells. For drug 2 that contains three components including Efavirenz, the drug effect on lymphocytes was increased by about 38% for patients that had been on antiretroviral drug treatment. Mathematical models were proposed and used in determining the coating effectiveness of antiretroviral drugs in the presence and absence of HIV. The use of the findings of this work by pharmaceutical industries may help in the search for more effective antiretroviral drugs for the treatment of HIV patients.