TITLE:
Facts about Endosalpingiosis
AUTHORS:
Min Hou, Lipai Chen, Jingping Yun
KEYWORDS:
Endosalpingiosis, Chronic Abdominal Pain, Serous Tumors, Tubal-Cell Origin, Carcinogenesis
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.5 No.10,
September
1,
2015
ABSTRACT: Endosalpingiosis was first described by Sampson in 1930. However, until
recently more and more studies show the convincing evidence that it most
probably originates from tubal cells. It has a close relationship with the
development of serous tumors, especially low-grade serous carcinoma. The lesion
does cause symptoms and signs, such as chronic abdominal pain or tumor-like
mass, though it is often found accidently for other gynecologic problems.
Occasionally atypical endosalpingiosis needs to be differentiated from a
malignancy when it appears in an unusual site with worrying morphologic
presentations or under some special circumstances. Owing to the facts that it
may evolve quietly and continuously towards serous tumors, and that the lesions
at different sites may evolve independently, the outcomes of its evolution can
eventually kill the patient. Therefore, a proper recognition of the lesion will
translate it into an adequate care for those patients. This review summarizes
the most recent findings and makes thoughtful comments.