TITLE:
Different Fetal and Neonatal Growth between Early- and Late-Onset Preeclampsia
AUTHORS:
Takashi Mitsui, Hisashi Masuyama, Eriko Eto, Etsuko Nobumoto, Kei Hayata, Yuji Hiramatsu
KEYWORDS:
Body Mass Index, Fetal Growth Restriction, Onset Period, Preeclampsia
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.5 No.9,
August
28,
2015
ABSTRACT: Preeclampsia is a heterogeneous disease, and there are major differences
in severity, fetal growth and poor placentation between early- and late-onset
preeclampsia. Here, we examined the effect of onset period on fetal and
neonatal growth in preeclampsia with a cross-sectional study including 102
pregnant women with preeclampsia visited Okayama University Hospital from 2009
to 2013. The subjects were retrospectively compared in terms of body mass index
(BMI), weight gain during pregnancy, complications, weeks of delivery, neonatal
body weight and BMI at birth, fetal growth restriction (FGR), small for
gestational age (SGA), pathological findings in the placenta, and infant’s
weight at 1 month after birth. Neonatal body weight and BMI at birth were
significantly lower and the extent of FGR and the frequency of SGA were higher
in early-onset group compared with late-onset group. Mean daily weight gain
during the neonatal period was significantly lower in the early-onset group
compared with the late-onset group, however the weight gain rate during the
neonatal period in the early-onset group was higher than that in late-onset
group. In conclusions, there are significant differences in fetal and neonatal
growth between early- and late-onset preeclampsia and the catch up for growth
might start during neonatal period.