TITLE:
Primary Thyroid Non-Hodgkin’s Lymphoma
AUTHORS:
Madiha Mahfoudhi, Khaled Khammassi, Imen Gorsane, Mounira El Euch, Sami Turki, Mamia Ben Salah, Taieb Ben Abdallah
KEYWORDS:
Thyroid Gland, Lymphoma, Immunohistochemistry
JOURNAL NAME:
Open Journal of Pathology,
Vol.5 No.4,
August
27,
2015
ABSTRACT: Primary non-Hodgkin’s lymphoma of the
thyroid gland was rarely described. We report the case of a 44-year-old man
admitted for an anterior neck swelling, hoarseness and dyspnea. The chest
radiograph showed a trachea deviation. He had no clinical, biological or
radiological sign of other lymphoma locations. Ultrasound examination of the
neck revealed a bilateral heterogeneous thyroid lesion. Cytology revealed
lymphoid cells having high nuclear-cytoplasmic ratio with multiple and
irregular nucleoli. An urgent thyroid surgery consisting of total thyroidectomy
had been performed since the presence of compressive signs due to the tumor.
The histopathological examination of a biopsy from the thyroid tissue
confirmed a high-grade non-Hodgkin’s lymphoma. Then, L-thyroxin substitution
therapy, chemotherapy and radiotherapy were initiated. A prolonged remission
was noted.