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Moodley, J.R., Hoffman, M., Carrara, H., Allan, B.R., Cooper, D.D., Rosenberg, L., Denny, L.E., Shapiro, S. and Williamson, A.L. (2006) HIV and Pre-Neoplastic and Neoplastic Lesions of the Cervix in South Africa: A Case-Control Study. BMC Cancer, 6, 135.
http://dx.doi.org/10.1186/1471-2407-6-135

has been cited by the following article:

• TITLE: Management of Cervical Intra Epithelial Neoplasia by Loop Electrosurgical Excision Procedure in a Low Resource Country: An Experience from the Yaoundé General Hospital, Cameroon

  AUTHORS: Jean Dupont Kemfang Ngowa, Anny Ngassam, Jovanny Fouogue Tsuala, Juny Metogo, Zacharie Sando, Angèle Kabeyene, Jean Marie Kasia

  KEYWORDS: Cervical Cancer, Cervical Intraepithelial Neoplasia, LEEP, Screening Cervical Cancer, Low Resource Country

  JOURNAL NAME: Open Journal of Obstetrics and Gynecology, Vol.5 No.9, August 25, 2015

  ABSTRACT: Background: Cervical cancer is the third most common cancer worldwide, and 80% of cases occur in the developing world. A critical component of effective cervical cancer screening programs is the ability to offer women appropriate and effective treatment for cervical intra epithelial neoplasia (CIN). Objectives: This study aimed at assessing the primary experience of management of CIN by Loop Electrosurgical Excision Procedure (LEEP) in a low resource country. Methods: We carried out a descriptive cross sectional study at the Yaoundé General Hospital in Cameroon. Results: Twenty three cases of CIN were treated by LEEP. Mean age of patients was 40.5 ± 9.9 years. Six (26.1%) patients were infected by the Human Immunodeficiency Virus (HIV). LEEP was indicated in 21 (91.30%) cases for CIN2 and CIN3. The mean duration of the surgical procedure was 10 ± 3 minutes. There was one (4.3%) complication (persistent cervical bleeding). Surgical margins were negative for dysplasia or invasive carcinoma in 18 (78.26%) cases and non-applicable in 5 (21.73%) cases (thermal artefacts of margins and cervicitis without CIN). One patient with micro invasive carcinoma on post-operative histology was treated by total hysterectomy. Cervical cytology was normal at 6 months post LEEP for 15 cases out of 16 (93.8%) patients who performed the test. One woman achieved pregnancy and delivered a term baby. Conclusion: Treatment of CIN by LEEP is feasible, safe and effective in our setting.