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Klandorf, H., Rathore, D., Iqbal, M., Shi, X., Simoyi, M. and Van Dyke, K. (2002) Acceleration of Tissue Aging in Chickens Caused by Oxidative Stress Using Allopurinol and Detected by Cellular Humoral Chemiluminescence. In: Van Dyke, K., Van Dyke, C. and Woodfork, K., Eds., Luminescence Biotechnology, CRC Press, New York, 393-407.

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• TITLE: The Non-Enzymatic Antioxidant and Level of Oxidative Stress of Tuberculosis Patients in Selected Treatment Center in Addis Ababa Ethiopia

  AUTHORS: Gebrehiwot Gebretsadik, Daniel Seifu, Getnet Yimer, M. K. C. Menon

  KEYWORDS: Tuberculosis, Non-Enzymatic Antioxidants, Oxidative Stress

  JOURNAL NAME: Journal of Tuberculosis Research, Vol.3 No.3, August 14, 2015

  ABSTRACT: Introduction: Non-enzymatic antioxidants are good scavengers of free radicals preventing their overproduction there by reducing the level of oxidative stress. This work was undertaken at Saint Peter TB specialized hospital and TekleHaimanot health center from March 2012 to May 2013.Aim: To determine changes in Non-Enzymatic Antioxidants and level of oxidative stress of tuberculosis Patients before and after taking anti tuberculosis treatment.Materials and Methods: In this comparative cross sectional study, a total of 210 individuals including: newly diagnosed TB patients as group-I (n = 70), TB patients who completed treatment as group-II (n = 70), and healthy volunteers as group-III (n = 70) were enrolled. Different methods were used to determine the parameters; vit-C (HPLC method), lipid peroxidation (thiobarbuituric acid method), and bilirubin (Colorimetric assay). Results: Vitamin-C (Vit-C) and of group-I showed a significant reduction (p