TITLE:
Thrombocytopenia, an Overlooked Hematological Derangement in Hair Dye Poisoning
AUTHORS:
Rizwan Naseer, AliRaza Ghani
KEYWORDS:
Hair Dye, Poisoning, PPD, Thrombocytopenia, Kala Pathar
JOURNAL NAME:
Case Reports in Clinical Medicine,
Vol.4 No.8,
August
10,
2015
ABSTRACT: Thrombocytopenia is a common hematological disorder characterized by abnormally low number of platelets in circulating blood from multiple causes. The fundamental mechanisms involved are: ineffective production of platelets by the bone marrow, accerlated destruction of platelets or platelet splenic sequestration. Hair dye, containing Paraphenyllinediamaine has been linked to allergic reaction, nephrotoxicity, mutagenicity and hematological derangements as anemia. A female showed a clinical spectrum of decreasing platelet count along with anemia due to oral ingestion of hair dye. It is important to consider thrombocytopenia in management plan as it may impact the clinical outcome.