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Sakai, M., Inoue, Y., Aoki, S., Sirasaka, T., Uehira, T., Takahama, S., et al. (2009) Follow-Up Magnetic Resonance Imaging Findings in Patients with Progressive Multifocal Leukoencephalopathy: Evaluation of Long-Term Survivors under Highly Active Antiretroviral Therapy. Japanese Journal of Radiology, 27, 69-77.

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• TITLE: Resistant Tremors and Unexplained Weight Loss Could Also Be a Sign of HIV

  AUTHORS: Mohammed Hamdy Ibrahim, Shivram Kumar, Janhavi Sirsat, Mohamed Khalid, Kiran Kumar

  KEYWORDS: Human Immunodeficiency Virus, Tremors, Progressive Multifocal Leukoencephalopathy

  JOURNAL NAME: Neuroscience and Medicine, Vol.6 No.3, July 30, 2015

  ABSTRACT: This case study is done to show a different type of presentation of a HIV (Human Immunodeficiency Virus) patient. Neurological symptoms in HIV are normally due to Progressive Multifocal Leukoencephalopathy (PML) which is a reactivated infection caused by John Cunningham virus (JC virus). The disease causes fatal demyelination of the central nervous system (CNS). This case presented a 51-year-old Nigerian man who complained of resistant tremors and unexplained weight loss. The patient was suspected to have HIV when a MRI scan revealed T2/FLAIR hyper intensity of white matter which was a sign of PML. HIV ELISA was done and came back with a positive result. PML presenting in the form of tremors is very rare and more research is required to focus on the neurological presentation of HIV.