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Nived, O., Bengtsson, A.A., Jönsen, A. and Sturfelt, G. (2008) Progressive Multifocal Leukoencephalopathy—The Importance of Early Diagnosis Illustrated in Four Cases. Lupus, 17, 1036-41.

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• TITLE: Resistant Tremors and Unexplained Weight Loss Could Also Be a Sign of HIV

  AUTHORS: Mohammed Hamdy Ibrahim, Shivram Kumar, Janhavi Sirsat, Mohamed Khalid, Kiran Kumar

  KEYWORDS: Human Immunodeficiency Virus, Tremors, Progressive Multifocal Leukoencephalopathy

  JOURNAL NAME: Neuroscience and Medicine, Vol.6 No.3, July 30, 2015

  ABSTRACT: This case study is done to show a different type of presentation of a HIV (Human Immunodeficiency Virus) patient. Neurological symptoms in HIV are normally due to Progressive Multifocal Leukoencephalopathy (PML) which is a reactivated infection caused by John Cunningham virus (JC virus). The disease causes fatal demyelination of the central nervous system (CNS). This case presented a 51-year-old Nigerian man who complained of resistant tremors and unexplained weight loss. The patient was suspected to have HIV when a MRI scan revealed T2/FLAIR hyper intensity of white matter which was a sign of PML. HIV ELISA was done and came back with a positive result. PML presenting in the form of tremors is very rare and more research is required to focus on the neurological presentation of HIV.