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Karagianis, J., Novick, D., Pecenak, J., Haro, J.M., Dossenbach, M., Treuer, T., Montgomery, W., Walton, R. and Lowry, A.J. (2009) Worldwide-Schizophrenia Outpatient Health Outcomes (W-SOHO): Baseline Characteristics of Pan-Regional Observational Data from More than 17,000 Patients. International Journal of Clinical Practice, 63, 1578-1588. http://dx.doi.org/10.1111/j.1742-1241.2009.02191.x

has been cited by the following article:

• TITLE: Differences in Baseline Characteristics of Patients Treated with Olanzapine or Other Antipsychotics in Japanese Patients with Acute Schizophrenia: A 1-Year Observational Study under Routine Clinical Practice in Japan

  AUTHORS: Michihiro Takahashi, Shinji Fujikoshi, Jumpei Funai, Levent Alev, Masaomi Iyo

  KEYWORDS: Schizophrenia, Baseline Characteristics, Olanzapine, Antipsychotics

  JOURNAL NAME: Open Journal of Psychiatry, Vol.5 No.3, July 27, 2015

  ABSTRACT: Objective: Baseline characteristics of acute schizophrenia patients were analyzed to identify differences in the baseline characteristics of patients treated with olanzapine monotherapy compared with those treated with other antipsychotic monotherapies. Methods: This prospective, naturalistic observational study was designed to evaluate discontinuation rates of olanzapine and non-olanzapine antipsychotic monotherapy in Japanese adult patients with acute schizophrenia. Results: A total of 1089 patients were assessed: 578 patients were treated with olanzapine, 487 with non-olanzapine atypical antipsychotics, and 24 with typical antipsychotics. The mean Clinical Global Impression-Severity (CGI-S) Schizophrenia, Brief Psychiatric Rating Scale (BPRS) total, and BPRS positive scores were higher in patients treated with olanzapine compared with most of the non-olanzapine treated patients. The majority of patients with a CGI-S Schizophrenia score of 7 (29/41 patients) as well as patients with a BPRS total score of 90 or higher (14/18 patients) were treated with olanzapine. On the other hand, physicians tended to prescribe antipsychotics other than olanzapine for patients with heavier body weight or diabetes mellitus. Conclusion: The present study demonstrated that olanzapine was more likely to be prescribed to patients with more severe schizophrenia symptoms. However, further studies are warranted to reach a definite conclusion.