Article citationsMore>>

Ryono, D.E. and Ondetti, M.A. (1982) US Patent No. 4321392.

has been cited by the following article:

• TITLE: Synthesis of (2S,4S)-2-Substituted-3- (3-Sulfanylpropanoyl)-6- Oxohexahydropyrimidine-4-Carboxylic Acids as Potential Antihypertensive Drugs

  AUTHORS: Andrei Ershov, Dmitry Nasledov, Igor Lagoda, Valery Shamanin

  KEYWORDS: Synthesis of (2S, 4S)-2-Substituted-3- (3-Sulfanylpropanoyl)-6- Oxohexahydropyrimidine-4-Carboxylic Acids as Potential Antihypertensive Drugs

  JOURNAL NAME: Journal of Materials Science and Chemical Engineering, Vol.3 No.6, June 11, 2015

  ABSTRACT: Proceeding from natural amino acid L-asparagine and commercially available aldehydes a stereoselective synthesis was developed of (2S,4S)-2-alkyl(aryl)-3-(3-sulfanylpropanoyl)-6-oxohexahy- dropyrimidine-4-carboxylic acids, potential antihypertensive drugs, inhibitors of the angiotensin converting enzyme.