TITLE:
Prevalence of Herpes Simplex Virus in Pregnant Women from Gangetic Plain Region of Allahabad, India
AUTHORS:
Omar Ahmed Omar Amar, Harish Kumar Bajaj, Neena Gupta, Ankit Singla, Harison Masih
KEYWORDS:
Herpes Simplex Virus, Seroprevalence, IgG, IgM, Quantitative ELISA
JOURNAL NAME:
Advances in Microbiology,
Vol.5 No.6,
June
8,
2015
ABSTRACT: Herpes Simplex Virus
(HSV) is a common pathogen that leads to lifelong latent infection and may be
associated with transmission from mother to their fetus. A total of 191 blood
samples of pregnant women were collected to check the prevalence of Herpes Simplex
Virus (HSV). It was observed that 124 (64.9%) and 04 (2.1%) samples were
positive for HSV IgG and HSV IgM, respectively. Seropositivity of HSV IgG
was the highest for third trimester and it was followed by second and first
trimester; while it was the highest for first trimester for HSV IgM and it was
followed by third and second trimester. Seroprevalence of HSV IgG and IgM was statistically insignificant (P > 0.05) according to
gestation age. A
significant correlation was observed between HSV IgG and age groups of pregnant
women; while it was insignificant for HSV IgM. Seroprevalence of
HSV IgG+ IgM- was
32 (53.3%), 61 (66.3%), and 27 (69.2%) for first, second and third trimester,
respectively. Seroprevalence of HSV IgG+ IgM+ group was 02 (3.3%), 01 (1.1%) and 01 (2.6%) for
first, second and third trimester, respectively. Seroprevalence of HSV IgG- IgM- group was 26 (43.3%), 30
(32.6%), and 11 (28.2%) for first, second and third trimester, respectively.