Article citationsMore>>
Grubber, J.M., Saunders, A.M., Crane-Gatherum, A.R., Scott, W.K., Martin, E.R., Haynes, C.S., Conneally, P.M., Small, G.W., Roses, A.D., Haines, J.L. and Pericak-Vance, M.A. (1999) Analysis of Association between Alzheimer’s Disease and the K Variant of Butyrylcholinesterase (BCHE-K). Neuroscience Letters, 269, 115-119.
http://dx.doi.org/10.1016/S0304-3940(99)00426-7
has been cited by the following article:
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TITLE:
Prevalence of Wild-Type Butyrylcholinesterase Genotype in Patients with Alzheimer’s Dementia
AUTHORS:
Beate Mueller, Georg Adler
KEYWORDS:
Butyrylcholinesterase, Alzheimer’s Disease, Genotype
JOURNAL NAME:
World Journal of Neuroscience,
Vol.5 No.3,
June
2,
2015
ABSTRACT: Approximately, two-thirds patients
with Alzheimer’s disease (AD) are reported to have homozygous wild-type
butyrylcholinesterase (BuChE) gene expression. It is associated with a higher
rate of hydrolysis of acetylcholine, which ultimately leads to increase in the
levels of BuChE in advanced stages of the disease. Rivastigmine, a dual
inhibitor of acetylcholinesterase (AChE) and BuChE, might be of additional
benefit in patients with AD with wild-type BuChE allele.