Article citationsMore>>
Chianella, C., Gragnaniello, D., Delser, P.M., Visentini, M.F., Sette, E., Tola, M.R., Barbujani, G. and Fuselliet, S. (2011) BCHE and CYP2D6 Genetic Variation in Alzheimer’s Disease Patients Treated with Cholinesterase Inhibitors. European Journal of Clinical Pharmacology, 67, 1147-1157.
http://dx.doi.org/10.1007/s00228-011-1064-x
has been cited by the following article:
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TITLE:
Prevalence of Wild-Type Butyrylcholinesterase Genotype in Patients with Alzheimer’s Dementia
AUTHORS:
Beate Mueller, Georg Adler
KEYWORDS:
Butyrylcholinesterase, Alzheimer’s Disease, Genotype
JOURNAL NAME:
World Journal of Neuroscience,
Vol.5 No.3,
June
2,
2015
ABSTRACT: Approximately, two-thirds patients
with Alzheimer’s disease (AD) are reported to have homozygous wild-type
butyrylcholinesterase (BuChE) gene expression. It is associated with a higher
rate of hydrolysis of acetylcholine, which ultimately leads to increase in the
levels of BuChE in advanced stages of the disease. Rivastigmine, a dual
inhibitor of acetylcholinesterase (AChE) and BuChE, might be of additional
benefit in patients with AD with wild-type BuChE allele.