TITLE:
Efficiency of Tamsulosin after Shockwave Lithotripsy for the Treatment of Lower Ureteric Stone: Alkaramah Teaching Hospital Experience, Iraq
AUTHORS:
Yarub Fadhil Hussein, Basim Jasim Abdulhussein, Abdulsalam Hatem Nawar, Redhwan Ahmed Al-Naggar
KEYWORDS:
Tamsulosin, Shockwave, Lithotripsy, Ureteric Stone, Iraq
JOURNAL NAME:
Open Journal of Urology,
Vol.5 No.5,
May
20,
2015
ABSTRACT: Background: Stone disease is a wide health
problem; certain drugs have been used as supplement with ESWL for the treatment
of symptomatic uncomplicated lower ureteric stone like Nefidipine, Alfuzosin
and Tamsulosin. The purpose of this study is to evaluate the efficacy of
Tamsulosin for the treatment of lower ureteric stone of 5 - 10 mm diameter
after ESWL. Methods: A total of 105 patients with lower ureteric stone of less
than 10 mm diameters were divided into two groups. Group 1 including 48
patients received 0.4 mg Tamsulosin and diclofenac sodium analgesia as needed
immediately after ESWL and continued until stone expulsion was confirmed up to
maximum of 30 days. Group 2 including 47 patients was given diclofenac sodium
only as needed after ESWL. Result: 46 of 49 patients in group 1 and 44 of 48
patients in group 2 ultimately passed stones. The number of ESWL sessions was
1.4 ± 0.6 in group 1 & 1.42 ± 0.75 in group 2. There were 10 patients who
needed analgesia after ESWL in group 1 and 17 patients in group 2. Visual
analogue scale pain severity score was 5.32 ± 1.23 and 6.41 ± 1.26 in group 1
and 2, respectively. The time to stone expulsion in group 1 and 2 was 8 ± 5.4
days and 12 ± 10.3 days, respectively. No significant complications or side
effects occurred. Conclusion: The use of Tamsulosin in combination with ESWL in
patients with lower ureteric stone of 5 - 10 mm was effective for reducing the
time to stone expulsion, decreasing need for analgesia, and facilitating stone
passage without significant improvement in stone free rate.