Article citationsMore>>
van Boxtel, M.P.J., Henskens, L.H.G., Kroon, A.A., Hofman, P.A.M., Gronenschild, E.H.B.M., Jolles, J. and de Leeuw, P.W. (2006) Ambulatory Blood Pressure, Asymptomatic Cerebrovascular Damage and Cognitive Function in Essential Hypertension. Journal of Human Hypertension, 20, 5-13.
http://dx.doi.org/10.1038/sj.jhh.1001934
has been cited by the following article:
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TITLE:
Could Ambulatory Blood Pressure Monitoring Be a Routine Investigation for Patients with Mild Cognitive Impairment?
AUTHORS:
Mohamed Hamdy Ibrahim, Tamer Taha Ismail Taha, Laila Adel Mohsen, Nisrin Moustafa Rizk El-Elsaadouni
KEYWORDS:
Mild Cognitive Impairment, Ambulatory Blood Pressure Monitoring, White Matter Lesions, Non-Dipper, MMSE
JOURNAL NAME:
Neuroscience and Medicine,
Vol.6 No.2,
May
15,
2015
ABSTRACT: Objectives: To study the ambulatory measured blood pressure (ABPM) profile in normotensive patients with mild cognitive impairment (MCI). Patients and Methods: The study was designed as a case control study including 50male patients with mild cognitive impairment in the age group of 30 - 50 years old. The control group included 30 volunteers with no cognitive impairment and in the same age group (30 - 50 years old) and same gender. Mini-mental estate examination, office and ABP monitoring (ABPM) and brain MRI scans were done for cases and controls. Results: Thirty patients (60%) with MCI revealed a non-dipper blood pressure pattern. Sleeping systolic blood pressure and sleeping systolic load were significantly higher in patients with MCI than in normal volunteers (p = 0.01). MRI brain showed more white matter lesions (WMLs) in patients with MCI than in normal volunteers; however, this didn’t reach significance level (p = 0.056). Conclusion: MCI in normotensive young adult patients could reflect an abnormal circadian blood pressure rhythm. Ambulatory blood pressure monitoring could be an essential investigation in young adult MCI patients.